Ortaca is one of the earliest known settlements that belonged to the Persian’s domination in 540 BC. This beautiful city's reigns had changed many times with the wars of Persian-Lydian and the wars of Persian-Hellen until it was conquered by Alexander the Great, King of Macedonia and the Commander in 334 BC. The conquering of this area took 200 years in his period. Ortaca was later controlled by the Egyptian Empire with the Queen of Egypt Cleopatra.
Ortaca that was ruled by the Roman Empire in 192 BC had participated in the Turkish territory with the Battle of Malazgirt between the Turkish army with the commander of Alpaslan the Seljuk and 200 thousand soldiers of the Commander of the Byzantine Emperor Romanos Diogenus.